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U.S. Transuranium and Uranium Registries News

Strom nominated as primary member on the Hanford Advisory Board

Daniel Strom, an adjunct professor at the USTUR, has been nominated to serve as a primary member on the Hanford Advisory Board, where he will represent local and regional public health. The Hanford Advisory Board provides “informed recommendations and advice to the U.S. Department of Energy (DOE), the U.S Environmental Protection Agency (EPA), and the Washington Department of Ecology (Ecology) on selected major policy issues related to the cleanup of the Hanford site.”(1) Dr. Strom is currently serving a two-year term as an alternate member of the board.

(1) https://www.hanford.gov/page.cfm/hab

Former USTUR PhD student selected for award

Sara Dumit has been selected to receive the 2022 John D. Boice Young Investigator Award from the National Council on Radiation Protection and Measurements. Dr. Dumit completed her PhD in pharmaceutical sciences at Washington State University. Her research utilized USTUR data to study the decorporation of plutonium from the human body during treatment with chelating agents such as DTPA. She continues to study actinide chelation and develop biokinetic models as a part of her work as a Health Physicist at Los Alamos National Laboratory (LANL). During 2021, Dr. Dumit also had the distinction of attending the Lindau Nobel Laureate Meeting. The meeting, which was held virtually, provided her with the unique opportunity to interact with Nobel Laureates from around the world.

For more information about Dr. Dumit’s selection for this award, visit the NCRP website.

2021 Newsletter

In December, the USTUR mailed its 2021 Registrant newsletter to living Registrants and deceased Registrants’ next of kin. This year’s newsletter discussed the unexpected opportunity provided by Covid-19 to focus on research involving existing data. Other topics included information about the Health Physics Society’s “Ask the Experts” webpage, and a status update on the USTUR’s plans to ask living Registrants to submit a urine sample for actinide analysis.

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Post-doctoral researcher receives award for paper about Manhattan Project Worker

Martin Šefl received an award from the Czech Society for Radiation Protection for his paper “Inhalation of soluble plutonium: 53-year follow-up of Manhattan Project worker,” which was published in the peer-reviewed journal Health Physics. The award was for the best work written by a young scientist in the field of radiation protection. His paper models the biokinetics of plutonium in a Registrant who was one of 26 Manhattan Project workers known informally as the “UPPU Club.” This group of plutonium-exposed workers were followed up by Los Alamos National Laboratory on a regular basis. Mr. Šefl’s work determined that the worker inhaled a combination of soluble and insoluble plutonium, and calculated doses associated with that intake.

Estimating organ doses from radium intakes: USTUR involvement

Maia Avtandilashvili was appointed as a member of the National Council on Radiation Protection and Measurements (NCRP) Scientific Committee (SC) 6-13 on methods and models for estimating organ doses from intakes of radium, and Sergei Tolmachev will serve as a subject matter expert for the committee. SC-13 will prepare a commentary that will discuss approaches for determining organ doses following intakes of radium. It will also describe methods for assessing uncertainties associated with dose assessments, and for estimating doses to workers without measurement data, based upon doses to workers with measurement data and similar work histories.

WSU student studies the effect of pH on bioaccumulation and trophic transfer of selenium in a northern Washington lake

A PhD candidate from the School of the Environment at WSU is conducting part of his research at the USTUR’s radiochemistry laboratory. Alexander Reyes is studying the amount of selenium in organisms collected from Omak Lake, the largest saltwater lake in Washington State. The lake is highly alkaline, which highly favors production of selenate ions in surface waters. Mr. Reyes’ research will assess the uptake of and bioaccumulation of selenium in organisms through different trophic levels of the food web, including various types of zooplankton, midges, invertebrates, and fish. Samples collected from Omak Lake were acid digested at the USTUR’s laboratory in preparation for inductively coupled plasma mass spectrometry (ICP-MS) analysis at WSU’s GeoAnalytical Lab in Pullman, WA.

USTUR faculty active at scientific meetings

During 2020, COVID restrictions meant that USTUR staff largely worked from home, and many scientific conferences were cancelled. Indeed, this slowed down certain operational aspects of the Registries, such as analyzing tissues for actinides. However, it also provided an unexpected opportunity for faculty to focus on research involving existing data. During 2021 alone, USTUR faculty have been preparing 11 papers for publication in scientific journals. Six will have a USTUR faculty member as the lead author, and six have already been submitted to and/or published in a journal. Additionally, scientific conferences have resumed using virtual, in-person, or hybrid formats. So far this year, USTUR faculty have authored eleven presentations at three conferences, and anticipate giving four additional presentations at the upcoming Radiation Research Meeting in October.

Journal Articles (Published or Accepted)

Avtandilashvili et al. Four-decade follow up of plutonium contaminated puncture wound treated with Ca-DTPA. DOI: 10.1088/1361-6498/ac04b8

Šefl et al. Inhalation of Soluble Plutonium: 53-year Follow-up of Manhattan Project Worker. DOI: 10.1097/HP.0000000000001396

Poudel et al. Long-term retention of plutonium in the respiratory tracts of two acutely-exposed workers: Estimation of bound fraction. DOI: 10.1097/HP.0000000000001311

Martinez et al. Radium dial workers: back to the future. DOI: 10.1080/09553002.2021.1917785

Conferences

Health Physics Society Midyear Workshop, May 23-26
Health Physics Society Annual Meeting, July 25-29
WSU College of Pharmacy and Pharmaceutical Sciences Research Day, August 13
Radiation Research Society Meeting, October 3-6

Maia Avtandilashvili featured on Health Physics Society’s Women in Radiation Protection website

USTUR Assistant Professor, Maia Avtandilashvili, was interviewed by the Health Physics Society’s (HPS) Public Information Committee. Dr. Avtandilashvili is an integral part of the USTUR’s research team, which she joined in 2012, and has published many interesting papers on the biokinetics of actinides in the human body. Continue reading to learn more about Maia’s career, from her time working at Tbilisi State University’s Radiocarbon and Low-level Radioactivity Laboratory to her current work at the USTUR.

Dr. Maia Avtandilashvili, PhD

Interview by Sara Dumit
Reproduced with permission of the Health Physics Society
Original article: http://hps.org/publicinformation/women3.html#Avtandilashvili

Dr. Maia Avtandilashvili is a nationally and an internationally recognized expert in radionuclide biokinetic modeling and internal dosimetry. Her research refines and validates the radiation dose assessment methods for actinide elements as the basis for reliable epidemiological studies, risk projection, and credible standards for radiological protection. Her expertise in biokinetic modeling is particularly critical to the field of health physics due to its importance to the assessment of internal radiation doses to workers and members of the general public.

Maia Avtandilashvili

Maia is a full member of the Health Physics Society (HPS) and a research assistant professor at the United States Transuranium and Uranium Registries (USTUR). Maia’s determination, resilience, and courage are inspirational—as she overcame many challenges while pursuing her dream to become a scientist.

Maia was born and raised in Tbilisi, the capital city of the Republic of Georgia, founded more than 15 centuries ago. She never had a doubt about who she wanted to be—a scientist—and later, when she started studying physics at school, a physicist. Maia was admitted to the physics department of Ivane Javakhishvili Tbilisi State University (TSU), the oldest and most respected higher-education institution in Georgia. In the third year, she chose to major in nuclear and particle physics and was offered a position of research assistant and, consequently, a graduate research project at TSU’s Radiocarbon and Low-level Radioactivity Laboratory (Radiocarbon Lab).

Maia graduated from TSU with a diploma (equivalent to an MS degree) with honors and continued working at TSU’s Radiocarbon Lab as a researcher. However, the huge political and economic changes due to disintegration of the Soviet Union drastically shifted the funding opportunities and priorities for science in Georgia. As a result, the funding for Maia’s graduate research was discontinued. However, she never quit pursuing her dream.

In the 1990s, TSU’s Radiocarbon Lab became involved in research projects to study the effects of the Chernobyl accident on the environment. Between 1997 and 2002, Maia participated in the International Atomic Energy Agency’s (IAEA) regional project on radioactivity in the Black Sea marine environment. During this project, she was awarded an IAEA fellowship, designed specifically for her, for on-the-job training in environmental radioactivity measurements with several leading German research institutions (Institute for Radiation Protection, BfS, Berlin; Institute for Radiation Hygiene, BfS, Munich; Institute for Chemical Research, Freiburg; Institute for Hydrology, BfG, Koblenz; and Institute for Fishery Ecology, BFAFi, Hamburg). The most exciting part of her training was a research cruise on the North and Baltic Seas to collect the sediment and biological samples for radioactivity measurements.

Maia Avtandilashvili on a research cruise, working for the IAEA.

In 2001, TSU’s Radiocarbon Lab established a long-term collaboration with the Health Physics Program at Idaho State University (ISU), and in 2006, Maia was offered a scholarship to pursue a PhD degree in health physics at ISU. Maia will always be grateful to Professor Rich Brey, who offered her this excellent opportunity to advance her career. While obtaining her PhD, she met Dr. Anthony (Tony) C. James, the USTUR director at that time, who became her PhD advisor and mentor. He interested her in internal dosimetry and the biokinetics of actinides. He was instrumental for Maia’s research in that she used the unique data from the USTUR to study long-term plutonium retention in the human respiratory tract. Sadly, Tony passed away just a few months prior to Maia’s PhD defense in 2011.

While at ISU, Maia was awarded the HPS Burton Moyer Fellowship for graduate studies. In addition, she received several HPS student travel grants that gave her an opportunity to attend the HPS annual meetings, present her research, and meet fellow health physicists. Maia is an active member of the HPS, as she is cofounder of the Georgian Health Physics Association (GHPA), an HPS chapter since 2007, and was a Program Committee member of the Columbia Chapter of the Health Physics Society (CCHPS) from 2017 to 2019.

After graduation from ISU, Maia joined the USTUR research team in Richland, Washington. The USTUR is the only tissue repository in the world that collects and preserves post-mortem tissue samples from workers in the US nuclear weapons complex. Maia is one of very few scientists with the knowledge, training, and skills required to maintain and evaluate this irreplaceable collection of samples required for further research on the effects of incorporated radioactive material. Maia’s research focuses on modeling of actinide biokinetics using this unique human data from former nuclear workers with accidental internal depositions of actinide elements. She is also responsible for management and population of the USTUR health physics database and has mentored graduate students and a postdoctoral researcher at the USTUR.

Maia’s work in the area of biokinetic modeling of actinide elements in humans has gained wide recognition among the international research community. She has been involved in international collaborative research projects with scientists from Karlsruhe Institute of Technology (Germany) and Public Health England (UK). In 2017, Maia was invited to become an associate member of the European Radiation Dosimetry Group (EURADOS) Working Group 7 on “Internal Dosimetry.”

Maia is actively involved as a subject-matter expert in the Million Person Study (MPS), the largest epidemiologic study of radiation exposure designed to evaluate radiation risks among healthy American workers and veterans. She serves on NCRP Scientific Committee (SC) 6-12 on development of models for brain dosimetry for internally deposited radionuclides. Maia also serves as an Editorial Board member of the journal Austin Biometrics and Biostatistics and as an ad hoc reviewer for several peer-reviewed journals, including Health Physics.

Maia has authored and coauthored numerous scientific articles in peer-reviewed journals including Health Physics, Radiation Protection Dosimetry, Journal of Radiological Protection, Radiation Research, Radiation and Environmental Biophysics, Radiocarbon, and various peer-reviewed abstracts in Health Physics. She has presented her research at numerous international and national conferences. Recently, she was an invited keynote speaker at the 12th International Conference on Health Effects of Incorporated Radionuclides, Fontenay-aux-Roses, France (2018), and was invited to give guest lectures on internal dosimetry and biokinetic modeling at Washington State University, Tri-Cities campus.

After almost 13 years of living in the United States on a nonresident status (starting with the student visa and, later, the H1-B work visa), Maia was granted permanent resident status in 2019. It was a challenging and exhausting experience to transition from a nonresident alien to a permanent resident status via the work-based immigration category. Maia’s immigration petition included reference letters from health physics experts from all around the world attesting to her expertise. Moreover, it included hundreds of pages showing evidence of her research’s value to the United States. Maia is grateful to everyone who supported her, especially Dr. Sergei Tolmachev, director of the USTUR. She is also thankful to the United States for recognizing her professional achievements and giving her the opportunity to pursue, permanently, an academic career in this great country.

We are fortunate to have such a brilliant member of the HPS and thank Maia for her scientific contributions and professional service to the health physics field!

Tony Riddell elected fellow of European radiological protection society

Tony Riddell has been elected a fellow of the Society for Radiological Protection in the United Kingdom. Mr. Riddell is an adjunct faculty member at the USTUR, and is the internal dosimetry group leader in the Radiation Hazards and Emergencies Department at Public Health England.

2020 Newsletter

In December, the USTUR mailed its 2020 Registrant newsletter to living Registrants and deceased Registrants’ next of kin. This year’s newsletter provided an update on the challenges and opportunities associated with Covid-19 work restrictions, as well as other activities at the USTUR.

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