The USTUR has completed its data quality objectives (DQO) document, which addresses the sample collection and data analysis needs in support of the United States Transuranium and Uranium Registries’ (USTUR) mission. The DQO process was originally developed by federal agencies to ensure that data of acceptable completeness and sufficient quality would be available to inform decisions about environmental cleanup. The USTUR generally does not make decisions based on its radiochemical measurement data, but rather uses the data it generates to quantitatively describe the biokinetics of uranium and transuranium elements in the human body. In this document, the USTUR presents its adaptation of the DQO process as described in the Multi-Agency Radiological Laboratory Analytical Protocols (MARLAP, 2004) Manual and American National Standards Institute’s ANSI/ANS-41.5-2012 standard as a key part of its Quality Assurance Project Plan (QAPP). Other parts of the QAPP can be found in other USTUR procedures and documents. The USTUR has chosen to adopt the methodology and terminology of MARLAP insofar as appropriate.